Part 1: A background for bone metastases

Chapter 1: Historical Concepts of Cancer Metastasis with Special Bone Reference;
Chapter 2: Cell Shedding by Tumors;
Chapter 3: The Vertebral Veins System, Caldwell Lecture, 1956;
Chapter 4: The Anatomy and Pathways of Skeletal Metastasis;
Chapter 5: The Mechanisms of Bone Metastasis and Bone Destruction by Tumor Cells;
Chapter 6: The Development of Skeletal Metastases;
Chapter 7: The clinical and laboratory consequences of metastatic cancer in bone;
Chapter 8: Cartilage Resistance to Invasion.

Part 2: The diagnosis of metastasis to bone

Chapter 9: The Pathologist and the Diagnosis of Bone Metastasis;
Chapter 10: The Radiologist and the Diagnosis of Bone Metastasis;
Chapter 11: Radionuclide scanning in bone metastasis;
Chapter 12: Computed Tomographic Evaluation of Bone and Soft Tissue Metastases;
Chapter 13: Comments from an orthopedic surgeon on the diagnosis of bone metastases in relation to management.

Part 3: Rehabilitation

Chapter 14: Patient Rehabilitation with Cancer.

Part 4: Chemical Therapy

Chapter 15: Pharmacokinetic studies and distribution with adriamycin;
Chapter 16: Chemotherapy of Bone Metastasis (I);
Chapter 17: Chemotherapy of Bone Metastasis (II);
Chapter 18: Hormonal Therapy of Metastatic Bone Disease;
Chapter 19: Analgesic Pain Management;

Part 5: Surgical Procedures

Chapter 20: The Management of Malignant Pathological Fractures.

Part 6: Radiotherapy

Chapter 21: The Philosophy and Economics of Palliative Radiotherapy for Bone Metastases;
Chapter 22: Wide-field irradiation of bone metastases;
Chapter 23: Palliation of Bone Metastases: Preliminary Report;
Chapter 24: Radiotherapy for Bone Metastases: The Hahnemann Experiment;
Chapter 25: Clinical and Radiobiological Bases of Concentrated Irradiation for Rapid Palliation of Bone Metastases;
Chapter 26: Single dosage and radiation therapy of short high dose fractionation for bone metastases;
Chapter 27: Quick Palliation in Private Practice;
Chapter 28: Bone Tolerance to Radiation Injury.